Abstract
McCune-Albright syndrome (MAS) consists of polyostotic fibrous dysplasia, precocious puberty, café-au-lait spots, and other endocrinopathies secondary to hyperactivity of various endocrine glands.
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Albright F, Butler AM, Hampton AO: Syndrome characterized by osteitis fibrosa disseminate, areas of pigmentation and endocrine dysfunction, with precocious puberty in females. N Engl J Med 216:727–747, 1937.
Anand MKN: Fibrous dysplasia. Emedicine, 2002. http://www.emedicine.com
Bareille P, Azcona C, Stanhope R: Multiple neonatal endocrinopathies in McCune-Albright syndrome. J Paediatr Child Health 35:315–318, 1999.
Benedict PH: Endocrine features in Albright’s syndrome (fibrous dysplasia of bone). Metabolism 1:30–45, 1962.
Bhansali A, Sharma BS, Sreenivasulu P, et al.: Acromegaly with fibrous dysplasia: McCune-Albright syndrome-Clinical studies in 3 cases and brief review of literature. Endocr J 50:793–799, 2003.
Boston BA: McCune-Albright syndrome. Emedicine, 2003. http://www.emedicine.com
Cabral CE, Guedes P, Fonseca T, et al.: Polyostotic fibrous dysplasia associated with intramuscular myxomas: Mazabraud’s syndrome. Skelet Radiol 27:278–282, 1998
Cavanah SF, Dons RF: McCune-Albright syndrome: how many endocrinopathies can one patient have? South Med J 86:364–367, 1993.
Coutant R, Lumbroso S, Rey R, et al.: Macroorchidism due to autonomous hyperfunction of Sertoli cells and Gs alpha gene mutation: an unusual expression of McCune-Albright syndrome in a prepubertal boy. J Clin Endocrinol Metab 86:1778–1781, 2001.
Danon M, Robboy SJ, Kim S, et al.: Cushing syndrome, sexual precocity, and polyostotic fibrous dysplasia (Albright syndrome) in infancy. J Pediatr 87:917–921, 1975.
De Sanctis C, Lala R, Matarazzo P: McCune-Albright syndrome: a longitudinal clinical study of 32 patients. J Pediatr Endocrinol Metab 12:817–826, 1999.
Eugster EA, Rubin SD, Reiter EO, et al.: Tamoxifen treatment for precocious puberty in McCune-Albright syndrome: a multicenter trial. J Pediatr 143:60–66, 2003.
Feuillan PP: The MAGIC Foundation. McCune-Albright syndrome Division. http://www.magicfoundation.org
Firat D, Stutzman L: Fibrous dysplasia of the bone. Review of twenty-four cases. Am J Med 44:421–429, 1968.
Foster CM, Feuillan P, Padmanabhan V, et al.: Ovarian function in girls with McCune-Albright syndrome. Pediatr Res 20:859–863, 1986.
Gross CW, Montgomery WW: Fibrous dysplasia and malignant degeneration. Arch Otolaryngol 85:97–101, 1967.
Gurler T, Alper M, Gencosmanoglu R: McCune-Albright syndrome progressing with severe fibrous dysplasia. J Craniofac Surg 9:79–82, 1998.
Harris WH, Dudley HR, Barry RJ: The natural history of fibrous dysplasia, an orthopaedic, pathologic and roentgenographic study. J Bone Joint Surg [Br] 44:207–233, 1962.
Isaia GC, Lala R, Defilippi C, et al.: Bone turnover in children and adolescents with McCune-Albright syndrome treated with Pamidronate for bone fibrous dysplasia. Calcif Tissue Int 71:121–128, 2002.
Lee PA, Van Dop C, Migeon CJ: McCune-Albright syndrome. Long-term follow-up. JAMA 256:2980–2984, 1986.
Lightner ES, Penny R, Frasier SD: Growth hormone excess and sexual precocity in polyostotic fibrous dysplasia (McCune-Albright syndrome): evidence for abnormal hypothalamic function. J Pediatr 87(6 pt 1):922–927, 1975.
McCune DJ, Bruch H: Osteodystrophia fibrosa: report of a case in which the condition was combined with precocious puberty, pathologic pigmentation of the skin and hyperthyroidism, with a review of the literature. Am J Dis Child 806–848, 1936.
Riminucci M, Fisher LW, Shenker A, et al.: Fibrous dysplasia of bone in the McCune-Albright syndrome: abnormalities in bone formation. Am J Pathol 151:1587–1600, 1997.
Schwartz DT, Alpert M: The malignant transformation of fibrous dysplasia. Am J Med Sci 247:1–20, 1964.
Shenker A, Weinstein LS, Moran A, et al.: Severe endocrine and nonendocrine manifestations of the McCune-Albright syndrome associated with activating mutations of stimulatory G protein GS. J Pediatr 123:509–518, 1993.
Shenker A, Weinstein LS, Sweet DE: An activating Gs alpha mutation is present in fibrous dysplasia of bone in the McCune-Albright syndrome. J Clin Endocrinol Metab 79:750–755, 1994.
Singer FR: Fibrous dysplasia of bone: the bone lesion unmasked. Am J Pathol 151:1511–1515, 1997.
Spiegel AM: The molecular basis of disorders caused by defects in G proteins. Horm Res 47:89–96, 1997.
Tinschert S, Geri H, Gewies A: McCune-Albright syndrome: clinical and molecular evidence of mosaicism in an unusual giant patient. Am J Med Genet 83:100–108, 1999.
Weinstein LS, Shenker A, Gejman PV, et al.: Activating mutations of the stimulatory G protein in the McCune-Albright syndrome. N Engl J Med 325:1688–1695, 1991.
Rights and permissions
Copyright information
© 2006 Humana Press Inc.
About this chapter
Cite this chapter
(2006). McCune-Albright Syndrome. In: Atlas of Genetic Diagnosis and Counseling. Humana Press. https://doi.org/10.1007/978-1-60327-161-5_120
Download citation
DOI: https://doi.org/10.1007/978-1-60327-161-5_120
Publisher Name: Humana Press
Print ISBN: 978-1-58829-681-8
Online ISBN: 978-1-60327-161-5
eBook Packages: MedicineMedicine (R0)