Abstract
During the past century, great progress has been made in the understanding of pulmonary hemodynamics and in the control of the normal and hypertensive pulmonary circulations. In large measure, the door to new knowledge was opened by the introduction and standardization of right heart catheterization in normal individuals and subsequently in patients with pulmonary hypertension. A byproduct of this remarkable progress has been the development of a classification schema for pulmonary hypertensive diseases based more on pathophysiology. Unfortunate experiments of nature giving rise to pulmonary hypertension epidemics related to appetite suppressant ingestion have nonetheless provided insights into its pathogenesis. The progress over the past century has laid the foundation for the gains in management that we have witnessed in recent years. In the near future, newer and less invasive technologies for detection and assessment, such as echocardiagraphic and magnetic resonance imaging, and novel, more effective medications are raising hopes for steadily improving outcomes.
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Fishman, A.P. (2008). Historical Perspective: A Century of Primary (Idiopathic) Pulmonary Hypertension. In: Hill, N.S., Farber, H.W. (eds) Pulmonary Hypertension. Contemporary Cardiology™. Humana Press. https://doi.org/10.1007/978-1-60327-075-5_1
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DOI: https://doi.org/10.1007/978-1-60327-075-5_1
Publisher Name: Humana Press
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