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Molecular Modeling: Considerations for the Design of Pharmaceuticals and Biopharmaceuticals

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Biopharmaceutical Drug Design and Development

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Abstract

In this chapter, we provide the reader with a broad overview of the tools and techniques commonly used in the fields of molecular modeling and computer-assisted drug design (CADD) and at the same time present context with respect to the discovery, design, and development of therapeutic agents. Note is also made to some of the challenges that lie at the cutting edge of these disciplines. We highlight a number of techniques and related software programs as they apply to the development of therapeutic pharmaceutical and biopharmaceutical agents.

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Authors and Affiliations

  1. Department of Medical Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA

    Philip D. Mosier PhD & Glen E. Kellogg PhD

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  1. Philip D. Mosier PhD
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Editors and Affiliations

  1. Pharmaceutical Sciences Graduate Programs Department of Pharmaceutics, School of Pharmacy, Virginia Commonwealth University, Richmond, VA

    Susanna Wu-Pong PhD (Director) (Director)

  2. Virginia Commonwealth University, Box 980581, Medical College of Virginia Campus, Richmond, VA, 23298

    Susanna Wu-Pong PhD (Director) (Director)

  3. Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV

    Yon Rojanasakul PhD (Professor of Pharmaceutical and Pharmacological Sciences) (Professor of Pharmaceutical and Pharmacological Sciences)

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Mosier, P.D., Kellogg, G.E. (2008). Molecular Modeling: Considerations for the Design of Pharmaceuticals and Biopharmaceuticals. In: Wu-Pong, S., Rojanasakul, Y. (eds) Biopharmaceutical Drug Design and Development. Humana Press. https://doi.org/10.1007/978-1-59745-532-9_13

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