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Animal Models in Functional Magnetic Resonance Imaging

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Sourcebook of Models for Biomedical Research

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Abstract

Functional magnetic resonance imaging (fMRI) has significantly advanced brain research, both in basic sciences as well as in translational and clinical studies. Animal models have been at the forefront of research into the mechanisms of magnetic resonance imaging (MRI) and fMRI. The use of animal models in fMRI has been particularly advantageous in preclinical and translational studies of various models of brain disease, and fundamental in the exploration of basic neuroscience questions, such as the mechanisms of perception, behavior, and cognition. This chapter describes the practical aspects of the use of animal models in fMRI studies of the brain.

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  1. Cerebral Microcirculation Unit, Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD

    Afonso C. Silva PhD & Bojana Stefanovic PhD

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  1. Oregon National Primate Research Center, Beaverton, OR

    P. Michael Conn PhD (Associate Director and Senior Scientist, Professor of Physiology and Pharmacology, Professor of Cell and Developmental Biology) (Associate Director and Senior Scientist, Professor of Physiology and Pharmacology, Professor of Cell and Developmental Biology)

  2. Oregon Health and Science University, Portland, OR

    P. Michael Conn PhD (Associate Director and Senior Scientist, Professor of Physiology and Pharmacology, Professor of Cell and Developmental Biology) (Associate Director and Senior Scientist, Professor of Physiology and Pharmacology, Professor of Cell and Developmental Biology)

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Silva, A.C., Stefanovic, B. (2008). Animal Models in Functional Magnetic Resonance Imaging. In: Conn, P.M. (eds) Sourcebook of Models for Biomedical Research. Humana Press. https://doi.org/10.1007/978-1-59745-285-4_51

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