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Genetic Basis of Olfactory Deficits

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Genomic Disorders

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Abstract

The completion of the human genome sequencing has opened new opportunities to better understand complex biological systems. In this realm, the human sense of smell is an excellent example of how genome analysis provides new information on genome organization and on deficits. Before the advent of genomic tools, the understanding of this highly sophisticated sensory neuronal pathway has been rather sketchy. In this chapter we summarize the relevant progress made in the last decade, and highlight the initial elucidation of two classes of olfactory deficits and their possible underlying genetic mechanisms.

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Authors and Affiliations

  1. Department of Molecular Genetics and the Crown Human Genome Center, Weizmann Institute of Science, Rehovot, Israel

    Idan Menashe MSc, Ester Feldmesser MSc & Doron Lancet PhD

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  1. Idan Menashe MSc
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  2. Ester Feldmesser MSc
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  3. Doron Lancet PhD
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  1. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX

    James R. Lupski MD, PhD  & Pawel Stankiewicz MD, PhD  & 

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Menashe, I., Feldmesser, E., Lancet, D. (2006). Genetic Basis of Olfactory Deficits. In: Lupski, J.R., Stankiewicz, P. (eds) Genomic Disorders. Humana Press. https://doi.org/10.1007/978-1-59745-039-3_7

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  • DOI: https://doi.org/10.1007/978-1-59745-039-3_7

  • Publisher Name: Humana Press

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  • Online ISBN: 978-1-59745-039-3

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