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Effects of Aliphatic Acids, Furfural and Phenolic Compounds on Debaryomyces hansenii CCMI 941

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Twenty-Sixth Symposium on Biotechnology for Fuels and Chemicals

Part of the book series: ABAB Symposium ((ABAB))

Abstract

Debaryomyces hansenii is a polyol overproducing yeast that can have a potential use for upgrading lignocellulosic hydrolysates. Therefore, the establishment of its tolerance to metabolic inhibitors found in hydrolysates is of major interest. We studied the effects of selected aliphatic acids, phenolic compounds, and furfural. Acetic acid favored biomass production for concentrations <6.0 g/L. Formic acid was more toxic than acetic acid and induced xylitol accumulation (maximum yield of 0.21 g/g of xylose). All tested phenolics strongly decreased the specific growth rate. Increased toxicity was found for hydroquinone, syringaldehyde, and 4-methylcatechol and was correlated to the compound’s hydrophobicity. Increasing the amount of furfural led to longer lag phases and had a detrimental effect on specific growth rate and biomass productivity.

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Author information

Authors and Affiliations

  1. Departamento de Biotecnologia, INETI, Estrada do Paço do Lumiar 22, 1649-038, Lisboa, Portugal

    Luís C. Duarte, Florbela Carvalheiro, Inês Neves & Francisco M. Gírio

Authors
  1. Luís C. Duarte
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  2. Florbela Carvalheiro
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  3. Inês Neves
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  4. Francisco M. Gírio
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Editor information

Editors and Affiliations

  1. Oak Ridge National Laboratory, USA

    Brian H. Davison  & Barbara R. Evans  & 

  2. National Renewable Energy Laboratory, USA

    Mark Finkelstein  & James D. McMillan  & 

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© 2005 Humana Press Inc.

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Duarte, L.C., Carvalheiro, F., Neves, I., Gírio, F.M. (2005). Effects of Aliphatic Acids, Furfural and Phenolic Compounds on Debaryomyces hansenii CCMI 941. In: Davison, B.H., Evans, B.R., Finkelstein, M., McMillan, J.D. (eds) Twenty-Sixth Symposium on Biotechnology for Fuels and Chemicals. ABAB Symposium. Humana Press. https://doi.org/10.1007/978-1-59259-991-2_36

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