Skip to main content

Darier’s Disease and Hailey-Hailey Disease

  • Chapter
Principles of Molecular Medicine

Abstract

These diseases are often discussed together because of some similarities in their histopathology. They map to different chromosomal locations and the clinical differences seem much more than the similarities. They will be discussed, in turn, in this chapter.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 74.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Selected References

  • Burge SM, Wilkinson JD. Darier-White disease: a review of the clinical features in 163 patients. J Am Acad Derm 1992; 40–50.

    Google Scholar 

  • Beck Jr. AL, Finocchio AF. Darter’s disease: a kindred with a large number. Br J Denn 1977; 97: 335–339.

    Article  Google Scholar 

  • Burge SM, Wilkinson JD, Miller AJ, Ryan TJ. The efficacy of an aromatic retinoid, Tigason (etretinate), in the treatment of inflammatory and noninflammatory dermatoses. Br J Dermatol 1981; 104: 675–679.

    Article  PubMed  CAS  Google Scholar 

  • Burge SM, Garrod DR. An immunohistological study of desmosomes in Darier’s disease and Hailey-Hailey disease. Br J Denn 1991; 124: 242–251.

    Article  CAS  Google Scholar 

  • Burge SM, Millard PR, et al. Hailey-Hailey disease: a widespread abnormality of cell adhesion. Brit J Denn 1991; 124: 329–332.

    CAS  Google Scholar 

  • Burge SM. Hailey-Hailey disease: the clinical features, response to treatment and prognosis. Br J Derm 1992; 126: 275–282.

    Article  CAS  Google Scholar 

  • Burge SM, Schomberg KH. Adhesion molecules and related proteins in Darier’s disease and Hailey-Hailey disease. Br J Derm 1992; 127: 335–343.

    Article  CAS  Google Scholar 

  • Caulfield JB, Wilgram GF. An electron-microscope study of dyskeratosis and acantholysis in Darter’s disease. J Invest Dermatol 1979; 41: 57–65.

    Google Scholar 

  • Crisp AJ, Payne Rowland CME, Adams J, et al. The prevalence of bone cysts in Darier’s disease: a survey of 31 cases. Clin Experiment Derm 1984; 9: 78–83.

    Article  CAS  Google Scholar 

  • Craddock N, Owen M, Burge S, Kurian B, Thomas P, McGuffin P. Familial cosegreation of major affective-disorder and Darier’ s disease (keratosis follicularis). Br J Psych 1994; 164: 355–358.

    Article  CAS  Google Scholar 

  • Demetree JW, Lang PG, St. Clair JT. Unilateral, linear, zosteriform epidermal nevus with acantholytic dyskeratosis. Arch Derm 1979; 115: 875–877.

    Article  PubMed  CAS  Google Scholar 

  • Dicken CH, Bauer EA, Hazen PG, et al. Isotretinoin treatment of Darier’ s disease. J Am Acad Dermatol 1982; 6: 721–726.

    Article  PubMed  CAS  Google Scholar 

  • Foresman PL, Goldsmith LA, Ginn L, Beck AL. Hemorrhagic Darier’ s Disease. Arch Derm 1993; 129: 511–512.

    Article  PubMed  CAS  Google Scholar 

  • Grover RW. Transient acantholytic dermatosis. Arch Dermatol 1970; 101: 426–434.

    Article  PubMed  CAS  Google Scholar 

  • Haake AR, Bartlett R, Polakowska R, Worobec S, Goldsmith LA. Is Darier’s disease a defect of the cell death pathway? J Invest Derm 1994; 102: 596.

    Google Scholar 

  • Hailey H, Hailey H. Familial benign chronic pemphigus. Arch Derm Syphil 1939; 39: 679–685.

    Article  Google Scholar 

  • Hedblad MA, Nakatani T, Beitner H. Ultrastructural changes in Darier’s disease induced by ultraviolet irradiation. Acta Derm Venereol 1991; 71: 108–112.

    PubMed  CAS  Google Scholar 

  • HogenEsch H, Gijbels MJJ, Offerman E, van Hooft J, van Bekkum DW, Zurcher C. A spontaneous mutation characterized by chronic proliferative dermatitis in C57BL mice. Am J Path 1993; 143: 972–982.

    PubMed  CAS  Google Scholar 

  • Ikeda S, Welsh EA et al. Localization of the gene whose mutations underlie HaileyHailey disease to chromosome 3q. Hum Molec Genet 1994; 3: 1147–1150.

    Article  PubMed  CAS  Google Scholar 

  • Kirtschig G, Gieler U, et al. Treatment of Hailey-Hailey disease by dermabrasion. J Amer Acad Derm 1993; 28: 784–786.

    Article  CAS  Google Scholar 

  • Matsuoka LY, Wortsman J, McConnachie P. Renal and testicular agenesis in a patient with Darier’s disease. Am J Med 1985; 78: 873–877.

    Article  PubMed  CAS  Google Scholar 

  • Munro CS. The phenotype of Darier’s disease: penetrance and expres- sivity in adults and children. Br J Dermatol 1992; 127: 126–130.

    Article  PubMed  CAS  Google Scholar 

  • Peluso AM, Bonifas JM, et al. Narrowing of the Hailey-Hailey disease gene region on chromosome 3q and identification of one kindred with a deletion in this region. Genomics 1995; 30: 77–80.

    Article  PubMed  CAS  Google Scholar 

  • Penrod JN, Everett MA, McCreight WG. Observations on keratosis follicularis. Arch Derm 1960; 82: 367–370.

    Article  PubMed  CAS  Google Scholar 

  • Wakem P, Ikeda S, Haake A, et al. Further sublocalization of the Darier disease gene on chromosome 12q and exclusion of NOS 1 as a candidate gene. J Invest Derm; 1996; 106: 365–367.

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1998 Springer Science+Business Media New York

About this chapter

Cite this chapter

Goldsmith, L.A., Epstein, E. (1998). Darier’s Disease and Hailey-Hailey Disease. In: Jameson, J.L. (eds) Principles of Molecular Medicine. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-726-0_76

Download citation

  • DOI: https://doi.org/10.1007/978-1-59259-726-0_76

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4757-6272-3

  • Online ISBN: 978-1-59259-726-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics