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fMRI in Neurodegenerative Diseases: From Scientific Insights to Clinical Applications

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Book cover fMRI Techniques and Protocols

Part of the book series: Neuromethods ((NM,volume 119))

Abstract

fMRI is a technology with great promise as a tool to probe abnormalities of brain activity in neurodegenerative diseases. The detection of functional brain abnormalities may be useful, in the appropriate clinical context, for early diagnosis, differential diagnosis, or prognostication. Prediction of response to treatment or therapeutic monitoring may also be possible with fMRI. In addition, fMRI has the potential to provide a variety of scientific insights that may have clinical relevance, including compensatory hyperactivation of brain circuits or genetic modulation of functional brain activity.

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Author information

Authors and Affiliations

  1. Gerontology Research Unit, Massachusetts General Hospital, 149 13th St., Suite 2691, Charlestown, MA, 02129, USA

    Bradford C. Dickerson

  2. Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy

    Federica Agosta & Massimo Filippi

  3. Department of Neurology, Division of Neuroscience, San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy

    Massimo Filippi

Authors
  1. Bradford C. Dickerson
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  2. Federica Agosta
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  3. Massimo Filippi
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Corresponding author

Correspondence to Bradford C. Dickerson .

Editor information

Editors and Affiliations

  1. Neuroimaging Research Unit, INSPE, Division of Neuroscience, San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy

    Massimo Filippi

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Dickerson, B.C., Agosta, F., Filippi, M. (2016). fMRI in Neurodegenerative Diseases: From Scientific Insights to Clinical Applications. In: Filippi, M. (eds) fMRI Techniques and Protocols. Neuromethods, vol 119. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-5611-1_23

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  • DOI: https://doi.org/10.1007/978-1-4939-5611-1_23

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-5609-8

  • Online ISBN: 978-1-4939-5611-1

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