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Advanced Imaging Techniques

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Advanced Imaging Techniques in Clinical Pathology

Part of the book series: Current Clinical Pathology ((CCPATH))

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Abstract

Microscopy techniques provide an efficient and unique approach to the study of fixed tissues and living cells and facilitate the definition and characterization of pathological conditions with high specificity and sensitivity. Recent advances in optical techniques and imaging methods have provided exciting insights into the field of translational research, extending possible applications for these techniques and enabling in vivo animal and human imaging of both physiological processes and pathological conditions. Here, we provide an overview of the recent data arising from such studies of electron and multiphoton microscopy, in vivo microendoscopy, and hybrid molecular imaging, such as positron emission tomography (PET)/computed tomography and PET/magnetic resonance and multimodality tracers. First, we give a brief introduction to the physical mechanisms underlying these imaging techniques. Then we introduce these advanced imaging techniques in more detail, with a description of how they are performed, what needs to be considered, and what practical advantages they can bring to in vivo characterization of human pathologies.

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Authors and Affiliations

  1. NAPLab - IRCCS SDN, Naples, Italy

    C. Cavaliere & M. Aiello

  2. Center for Advanced Biomaterials for Health Care (CABHC), Istituto Italiano di Tecnologia, Naples, Italy

    E. Torino & V. Mollo

  3. Institute of Human Anatomy, Seconda Università degli Studi di Napoli, Naples, Italy

    L. Marcello

  4. U.O. Fisica Sanitaria - P.O. “V. Faze”, Lecce, Italy

    D. De Luca

  5. Department of Radiological Sciences, Seconda Università degli Studi di Napoli, Naples, Italy

    N. Pignatelli di Spinazzola & V. Parlato

  6. Center for Advanced Biomaterials for Health Care CABHC - Istituto Italiano di Tecnologia, Naples, Italy

    P. A. Netti

  7. CRIB – Centro di Ricerca Interdipartimentale sui Biomateriali – Università Federico II di Napoli, Naples, Italy

    P. A. Netti

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  1. C. Cavaliere
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  2. M. Aiello
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  3. E. Torino
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  5. L. Marcello
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  6. D. De Luca
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  7. N. Pignatelli di Spinazzola
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  9. P. A. Netti
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Correspondence to C. Cavaliere .

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Editors and Affiliations

  1. College of Science and Technology, Temple University, Philadelphia, Pennsylvania, USA

    Francesco M. Sacerdoti

  2. College of Science and Technology, Temple University, Philadelphia, Pennsylvania, USA

    Antonio Giordano

  3. NAPLAB, IRCCS SDN NAPLAB, Naples, Italy

    Carlo Cavaliere

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Cavaliere, C. et al. (2016). Advanced Imaging Techniques. In: Sacerdoti, F., Giordano, A., Cavaliere, C. (eds) Advanced Imaging Techniques in Clinical Pathology. Current Clinical Pathology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3469-0_6

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