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Glycopolymer-Grafted Polymer Particles for Lectin Recognition

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1367))

Abstract

Glycopolymers bearing carbohydrates have an advantage in protein recognition that is attributable to the multivalent effect (cluster effect) of side-chain carbohydrates. A variety of surface-modified polymer particles have been prepared concurrently with the development of new synthetic technology. Here we describe a synthetic method of glycopolymer-grafted polymer particles by surface-initiated living radical polymerization, i.e., atom-transfer radical polymerization (ATRP) and photoiniferter polymerization, for specific lectin recognition.

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Acknowledgments

This work was partially supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan (Nos. 20850005 and 23750119).

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Correspondence to Michinari Kohri .

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Kohri, M., Taniguchi, T., Kishikawa, K. (2016). Glycopolymer-Grafted Polymer Particles for Lectin Recognition. In: Sun, XL. (eds) Macro-Glycoligands. Methods in Molecular Biology, vol 1367. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3130-9_11

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  • DOI: https://doi.org/10.1007/978-1-4939-3130-9_11

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-3129-3

  • Online ISBN: 978-1-4939-3130-9

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