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Approaches to Study Human T Cell Development

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T-Cell Development

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1323))

Abstract

Not only is human T cell development characterized by unique changes in surface marker expression, but it also requires specific growth factors and conditions to mimic and study T cell development in vitro. In this chapter, we provide an overview of the specific aspects that need attention when performing T cell differentiation cultures with human progenitors.

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References

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Author information

Authors and Affiliations

  1. The Department of Clinical Chemistry, Microbiology and Immunology, Faculty of Medicine and Health Sciences, Ghent University Hospital, Ghent University, De Pintelaan 185 Blok A-4, 9000, Ghent, Belgium

    Anne-Catherine Dolens, Inge Van de Walle & Tom Taghon

Authors
  1. Anne-Catherine Dolens
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  2. Inge Van de Walle
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  3. Tom Taghon
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Corresponding author

Correspondence to Tom Taghon .

Editor information

Editors and Affiliations

  1. Laboratory of Immune Cell Biology, National Institutes of Health National Cancer Institute, Bethesda, Maryland, USA

    Rémy Bosselut

  2. Laboratory of Immune Cell Biology, National Institutes of Health National Cancer Institute, Bethesda, Maryland, USA

    Melanie S. Vacchio

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© 2016 Springer Science+Business Media New York

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Dolens, AC., Van de Walle, I., Taghon, T. (2016). Approaches to Study Human T Cell Development. In: Bosselut, R., S. Vacchio, M. (eds) T-Cell Development. Methods in Molecular Biology, vol 1323. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2809-5_20

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  • DOI: https://doi.org/10.1007/978-1-4939-2809-5_20

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-2808-8

  • Online ISBN: 978-1-4939-2809-5

  • eBook Packages: Springer Protocols

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