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Sirenomelia

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Atlas of Genetic Diagnosis and Counseling

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Abstract

Sirenomelia is a rare malformation sequence characterized by a partial or complete fusion of the lower limbs associated with urogenital, anal, lower spine, and other anomalies. The term sirenomelia comes from “siren” or “mermaid” because of the characteristic fusion of the lower extremities. Because of its physical resemblance to the mythical mermaid, the topic of sirenomelia has fascinated public for centuries. Sirenomelia occurs in approximately 1 in 60,000 births.

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Authors and Affiliations

  1. Medical Genetics, Shriners Hospitals for Children, Perinatal and Clinical Genetics, Department of Pediatrics, LSU Health Sciences Center, Shreveport, LA, USA

    Harold Chen

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  1. Harold Chen
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Chen, H. (2017). Sirenomelia. In: Atlas of Genetic Diagnosis and Counseling. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2401-1_217

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  • DOI: https://doi.org/10.1007/978-1-4939-2401-1_217

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-2400-4

  • Online ISBN: 978-1-4939-2401-1

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