Abstract
Invasive infection with group A streptococci (GAS) usually occurs in single, isolated cases but time/place clusters of infection featuring single or multiple M-serotypes have been reported in community settings from the UK and elsewhere in recent years3,6. Additionally, nation-wide increases in the prevalence of certain serotypes (notably M-types 1 and 3) in several parts of the world have been associated with increased reports of serious infection1, 2, 7. We describe two clusters of invasive GAS infection in the UK, principally featuring M-type 1, which mark a resurgence of clinical disease at a time of increasing prevalence of the type.
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References
Anderson, M.E. and Ronne, T. (1995). Group A streptococcal bacteraemias in Denmark 1987–89. J. Infect. 31:33–37.
Bucher, A., Martin, P.R. et al. (1992). Spectrum of disease in bacteraemic patients during a Streptococcus pyogenes serotype M-1 epidemic in Norway in 1988. Eur. J. Clin. Microbiol. Infect. Dis. 11: 416–426.
Cartwright, K., Logan, M. et al. (1995). A cluster of cases of streptococcal necrotizing fasciitis in Gloucestershire. Epidemiol. Infect. 115: 387–397.
Davies, H.D., Low, D.E. et al. (1995). Evaluation of short-course therapy with cefixime or rifampin for eradication of pharyngeally carried group A streptococci. Clin. Infect. Dis. 21: 1294–1296.
Musser, J.M., Kapur, V., Szeto, J., Pan, X., Swanson, D.S. and Martin, D. (1995). Genetic diversity and relationships among Streptococcus pyogenes strains expressing serotype Ml protein: recent intercontinental spread of a subclone causing episodes of invasive disease. Infect. Immun 63: 994–1003.
Schwartz, B., Elliott, J.A. et al. (1992). Clusters of invasive group A streptococcal infections in family, hospital and nursing home settings. Clin. Infect. Dis. 15: 277–284.
Schwartz, B., Facklam, R.R. and Breiman, R.F. (1990). Changing epidemiology of group A streptococcal infection in the USA. Lancet 336: 1167–1171.
Stanley, J., Linton, D., Desai, M., Efstratiou, A. and George, R. (1995). Molecular subtyping of prevalent M serotypes of Streptococcus pyogenes causing invasive disease. J. Clin. Microbiol. 33: 2850–2855.
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© 1997 Springer Science+Business Media New York
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Barnham, M., Weightman, N., Chapman, S., Efstratiou, A., George, R.C., Stanley, J. (1997). Two Clusters of Invasive Streptococcus pyogenes Infection in England. In: Horaud, T., Bouvet, A., Leclercq, R., de Montclos, H., Sicard, M. (eds) Streptococci and the Host. Advances in Experimental Medicine and Biology, vol 418. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1825-3_17
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DOI: https://doi.org/10.1007/978-1-4899-1825-3_17
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