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Synthesis of Organofluorine Compounds

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Organofluorine Chemistry

Part of the book series: Topics in Applied Chemistry ((TAPP))

Abstract

Fluoroorganic chemistry is virtually a man-made subject. Indeed, perfluorocarbon chemistry—which straddles organic and inorganic chemistry—is sometimes facetiously referred to as unnatural product chemistry. Fluorometabolites do occur in nature, but they are few in number and only monofluorides have been detected so far.1 The best known is the plant metabolite CH2FCO2H (see Chapter 1); the other nine include the related compounds CH2FCOCH3, 2-fluorocitric acid, F(CH2) n CO2H (n = 9, 13, 15), and F(CH2)8CH=CH(CH2)7CO2H. The most intriguing by far is nucleo-cidin (1), an antibiotic fluoro-sugar derivative produced by the microorganisms Streptomyces calvus.

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Author information

Authors and Affiliations

  1. Department of Chemistry, The University of Manchester Institute of Science and Technology, Manchester, M60 1QD, England

    R. E. Banks

  2. Editorial Office of the Journal of Fluorine Chemistry, 30 Grassmoor Road, Kings Norton, Birmingham, B38 8BP, England

    J. C. Tatlow

Authors
  1. R. E. Banks
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  2. J. C. Tatlow
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Editor information

Editors and Affiliations

  1. The University of Manchester Institute of Science and Technology (UMIST), Manchester, UK

    R. E. Banks

  2. DuPont Central Research & Development, Wilmington, Delaware, USA

    B. E. Smart

  3. Editorial Office of the Journal of Fluorine Chemistry, Birmingham, UK

    J. C. Tatlow

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© 1994 Springer Science+Business Media New York

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Banks, R.E., Tatlow, J.C. (1994). Synthesis of Organofluorine Compounds. In: Banks, R.E., Smart, B.E., Tatlow, J.C. (eds) Organofluorine Chemistry. Topics in Applied Chemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1202-2_2

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  • DOI: https://doi.org/10.1007/978-1-4899-1202-2_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1204-6

  • Online ISBN: 978-1-4899-1202-2

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