Abstract
Radiopharmaceuticals containing complex functional groups are playing an increasing role in diagnostic nuclear medicine due to new developments in the instrumentation used for single-photon emission computerized tomography (SPECT)1 and positron emission tomography (PET).2 These computerized systems permit noninvasive, in vivo, three-dimensional imaging of organs after administration of appropriate agents labeled with short-lived nuclides.3 The techniques are used for in vivo pharmacokinetics, organ imaging, evaluation of organ function, and physiological mapping. They complement the traditional X-ray scan and are’partially responsible for the tremendous upsurge in the use of radiopharmaceuticals in hospitals today.
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Kabalka, G.W., Goodman, M.M. (1991). Synthesis of Radiopharmaceuticals Via Organoboranes. In: Emran, A.M. (eds) New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0626-7_27
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DOI: https://doi.org/10.1007/978-1-4899-0626-7_27
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