Skip to main content
SpringerLink
Log in

Long-Term Effects of Firing on Excitability of Hippocampal CA1 Neurons

  • Chapter
Cellular Mechanisms of Conditioning and Behavioral Plasticity

  • 62 Accesses

Abstract

Backfiring a hippocampal CA 1 cell by stimulation of its axon can, under certain circumstances, cause it to become less excitable to synaptic input (Dunwiddie and Lynch, 1978). We have investigated the basis of this lowered excitability.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Andersen P., Eccles, J. C., and Løyning, Y., 1964, Pathway of postsynaptic inhibition in the hippocampus, J. Physiol. (Lond.) 27: 608–619.

    CAS  Google Scholar 

  • Dunwiddie, T., and Lynch, G., 1978, Long-term potentiation and depression of synaptic responses in the rat hippocampus: Localization and frequency dependency, J. Physiol. (Lond.) 276: 353–367.

    CAS  Google Scholar 

  • Halliwell, J. V., and Adams, P. R., 1982, Voltage-clamp analysis of muscarinic excitation in hippocampal neurons, Brain Res. 250: 71–92.

    Article  PubMed  CAS  Google Scholar 

  • Zbicz, K. L., and Weight, F. F., 1985, Transient voltage and calcium-dependent outward currents in hippocampal CA3 pyramidal neurons, J. Neurophysiol. 53: 1038–1058.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physiology, University of Auckland, Auckland, New Zealand

    S. Pockett

  2. Department of Human Physiology, Royal Holloway and Bedford New College, Egham, TW20 OEX, England

    O. C. J. Lippold

Authors
  1. S. Pockett
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. O. C. J. Lippold
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Mental Retardation Research Center, Brain Research Institute, University of California, Los Angeles, 90024, Los Angeles, California, USA

    Charles D. Woody

  2. Section on Neural Systems, Laboratory of Biophysics, IRP, National Institute of Neurological Communicative Diseases and Stroke, National Institutes of Health at the Marine Biological Laboratory, 02543, Woods Hole, Massachusetts, USA

    Daniel L. Alkon

  3. Center for Neurobiology of Learning and Memory, University of California, Irvine, Irvine, California, USA

    James L. McGaugh

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Springer Science+Business Media New York

About this chapter

Cite this chapter

Pockett, S., Lippold, O.C.J. (1988). Long-Term Effects of Firing on Excitability of Hippocampal CA1 Neurons. In: Woody, C.D., Alkon, D.L., McGaugh, J.L. (eds) Cellular Mechanisms of Conditioning and Behavioral Plasticity. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9610-0_38

Download citation

  • DOI: https://doi.org/10.1007/978-1-4757-9610-0_38

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9612-4

  • Online ISBN: 978-1-4757-9610-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation