Summary
Anti-neutrophil cytoplasmic antibodies (ANCA) were observed in 31 out of 68 sera (45%) from Ulcerative Colitis (UC) patients and in 13 out of 38 Crohn’s Disease (CD) sera (34%). The presence of ANCA was not related to disease activity, nor to the localization of the disease manifestations. By Western Blotting ANCA showed reactivity with either lactoferrin, polypeptides occurring as a doublet of 66/67 kD MW, or polypeptides occurring as a doublet of 63/54 kD MW.
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Mulder, A.H.L., Broekroelofs, J., Horst, G., Limburg, P.C., Nelis, G.F., Kallenberg, C.G.M. (1993). Antineutrophil Antibodies in Inlammatory Bowel Disease Recognize Different Antigens. In: Gross, W.L. (eds) ANCA-Associated Vasculitides. Advances in Experimental Medicine and Biology, vol 336. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9182-2_94
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DOI: https://doi.org/10.1007/978-1-4757-9182-2_94
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