The Cholinergic Hypothesis of Geriatric Cognitive Dysfunction”: Consensus Meeting. January 24–25, 1993, Brescia, Italy

Abstract

The basal forebrain cholinergic system (BFCS) appears to be the major source of cortical cholinergic innervation. Anatomical, physiological and behavioral experiments are now beginning to unravel some of the mechanisms linking this system to complex behavior, aging and neurodegenerative processes. The BFCS has been suggested to be particularly involved in cortical activation and reorganization, learning and memory, attention, and development.

Editors’ Note

While not actually a part of the information presented at the AD/PD’93 conference, the following is relevant to the topic of this book, since a large portion of the co-signers also participated in the AD/PD conference, and since the topic deals with the so-called “Cholinergie Hypotheses of Alzheimer’s Disease”. This summary report is based on a two-day consensus meeting organized by Professors Spano and Trabucchi in Brescia, Italy, on January 24–25, 1993. The editors thought it would be appropriate to include this summary with the proceedings of the AD/PD ‘83 meeting.