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Ubiquinol

An Endogenous Lipid-Soluble Antioxidant in Animal Tissues

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Free Radicals, Oxidative Stress, and Antioxidants

Part of the book series: NATO ASI Series ((NSSA,volume 296))

Abstract

Ubiquinone (UQ) was first described by Morton and colleagues (Festenstein et al., 1955) as a quinone with a ubiquitous occurrence in various tissues, hence its name (Figure 1). Two years later, Crane et al. (1957) identified a quinone that was proposed to be a component of the mitochondrial respiratory chain, functioning as a coenzyme for electron transfer from Complexes I and II to Complex III (Figure 2). As such, it was given the name coenzyme Q. Its structure was determined by Folkers and collegues (Wolf et al., 1958) and found to be identical to ubiquinone.

This presentation was based on a chapter by the same authors, to appear in Reactive Oxygen Species in Biological Systems: Selected Topics, edited by D.L. Gilbert and C.A Colson, Plenum Publishing Corporation, New York, 1998. (Reproduced with permission of the publishers).

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Authors and Affiliations

  1. Department of Biochemistry, Arrhenius Laboratories for Natural Sciences, Stockholm University, S-106 91, Stockholm, Sweden

    Patrik Andrée, Gustav Dallner & Lars Ernster

  2. Clinical Research Center NOVUM, Karolinska Institute, S-141 86, Huddinge, Sweden

    Patrik Andrée & Gustav Dallner

Authors
  1. Patrik Andrée
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  2. Gustav Dallner
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  3. Lars Ernster
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  1. Akdeniz University, Antalya, Turkey

    Tomris Özben

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© 1998 Springer Science+Business Media New York

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Andrée, P., Dallner, G., Ernster, L. (1998). Ubiquinol. In: Özben, T. (eds) Free Radicals, Oxidative Stress, and Antioxidants. NATO ASI Series, vol 296. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-2907-8_26

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  • DOI: https://doi.org/10.1007/978-1-4757-2907-8_26

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4419-3292-1

  • Online ISBN: 978-1-4757-2907-8

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