Abstract
The present chapter summarizes our findings with lipoxins (LX) in spasmogenic assays and in the intact microvasculature of the hamster cheek pouch. The initial observations1,2 were made in experiments using lipoxins isolated from human leukocytes. With the aid of synthetic compounds3, it has been possible to further explore the pharmacodynamics and structure activity relationships for lipoxins in smooth muscle preparations.
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Dahlén, SE. et al. (1988). Actions of Lipoxin A4 and Related Compounds in Smooth Muscle Preparations and on the Microcirculation in Vivo. In: Wong, P.YK., Serhan, C.N. (eds) Lipoxins. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0937-7_9
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DOI: https://doi.org/10.1007/978-1-4757-0937-7_9
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