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Morphological Aspects of the Local Immune Response to Influenza in Rats

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In Vivo Immunology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 149))

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Abstract

Influenza viruses attack the ciliary epithelial cells of the respiratory tract, where they reproduce causing a sequence of clinically manifested symptoms with prevalency of general intoxication. The absence of viraemia and the restricted epitheliotropism of influenza makes this virus a very convenient model for studying the different aspects of the mucosal immunity in respiratory tract. The local anti-influenza defense at this site involves the respiratory epithelial cells and other nonimmunological factors as well as the components of the local immune apparatus, namely, mucosal lymphoid elements and regional lymph nodes (LN).

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© 1982 Plenum Press, New York

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Angelov, Z.R., Angelova, L.A. (1982). Morphological Aspects of the Local Immune Response to Influenza in Rats. In: Nieuwenhuis, P., van den Broek, A.A., Hanna, M.G. (eds) In Vivo Immunology. Advances in Experimental Medicine and Biology, vol 149. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-9066-4_31

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  • DOI: https://doi.org/10.1007/978-1-4684-9066-4_31

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-9068-8

  • Online ISBN: 978-1-4684-9066-4

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