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The Effect of Stimulated Macrophages on High Endothelial Venules and Germinal Centres in Lymph Nodes of Rat

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In Vivo Immunology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 149))

Abstract

Six weeks after interruption of afferent lymphatic vessels popliteal lymph nodes are severely depleted of macrophages (Mø) and have no germinal centres, lymphoblasts or plasma cells. The endothelial cells of the high endothelial venules (HEV) are flattened, have a poor affinity for pyronin, show an inactive nucleus and a paucity of protein synthesizing and secreting cell organelles. Lymphocytes in transit are absent in these venules (1, 2).

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References

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Authors and Affiliations

  1. Department of Electron Microscopy, Medical Faculty, Free University, Amsterdam, The Netherlands

    H. R. Hendriks, H. A. B. v. Hemert & M. v. d. Heijden

Authors
  1. H. R. Hendriks
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  2. H. A. B. v. Hemert
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  3. M. v. d. Heijden
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Editor information

Editors and Affiliations

  1. University of Groningen, Groningen, The Netherlands

    Paul Nieuwenhuis  & A. A. van den Broek  & 

  2. NCI-Frederick Cancer Research Facility, Frederick, Maryland, USA

    M. G. Hanna Jr.

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© 1982 Plenum Press, New York

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Hendriks, H.R., v. Hemert, H.A.B., v. d. Heijden, M. (1982). The Effect of Stimulated Macrophages on High Endothelial Venules and Germinal Centres in Lymph Nodes of Rat. In: Nieuwenhuis, P., van den Broek, A.A., Hanna, M.G. (eds) In Vivo Immunology. Advances in Experimental Medicine and Biology, vol 149. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-9066-4_28

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  • DOI: https://doi.org/10.1007/978-1-4684-9066-4_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-9068-8

  • Online ISBN: 978-1-4684-9066-4

  • eBook Packages: Springer Book Archive

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