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Trophic Effects of Endogenous and Exogenous Pancreozymin Upon the Exocrine and Endocrine Pancreas

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Gastrointestinal Hormones and Pathology of the Digestive System

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 106))

Abstract

Pancreozymin is known to have a trophic effect on the exocrine pancreas. Feeding rats or chicks with soybeans causes hypertrophy of the pancreas and this effect is ascribed to trypsin inhibitor contained in soybeans. Furthermore, it is now accepted by many authors that the pancreatotrophic effect of trypsin inhibitor is mediated by CCK-PZ released from the gut mucosa.1,2

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References

  1. Green GM, Lyman RL: Feedback regulation of pancreatic enzyme secretion as a mechanism for trypsin inhibitor-induced hypersecretion in rats. Proc. Soc. Exp. Biol. Med. 140, 6–12, 1972

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© 1978 Plenum Press, New York

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Fujita, T., Matsunari, Y., Koga, Y., Sato, K., Hayashi, M. (1978). Trophic Effects of Endogenous and Exogenous Pancreozymin Upon the Exocrine and Endocrine Pancreas. In: Grossman, M., Speranza, V., Basso, N., Lezoche, E. (eds) Gastrointestinal Hormones and Pathology of the Digestive System. Advances in Experimental Medicine and Biology, vol 106. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7248-6_18

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  • DOI: https://doi.org/10.1007/978-1-4684-7248-6_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7250-9

  • Online ISBN: 978-1-4684-7248-6

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