Abstract
The endogenous 31-amino acid peptide β-endorphin has been reported to both increase (1–6) and suppress (7,8) mitogen-induced T lymphocyte proliferation. No effect of β-endorphin on B cell proliferation has been noted (2). However, β-endorphin has been shown to decrease antibody production as measured by the plaque-forming cell response (5,9). These results suggest that β-endorphin may inhibit immunoglobulin synthesis by modulating T cell function.
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© 1991 Plenum Press, New York
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Hemmick, L.M., Bidlack, J.M. (1991). Endorphin Peptides Enhance Mitogen-Induced T Cell Proliferation Which has been Suppressed by Prostaglandins. In: Friedman, H., Specter, S., Klein, T.W. (eds) Drugs of Abuse, Immunity, and Immunodeficiency. Advances in Experimental Medicine and Biology, vol 288. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5925-8_23
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DOI: https://doi.org/10.1007/978-1-4684-5925-8_23
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