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Catalases—With and Without Heme

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Oxygen Radicals in Biology and Medicine

Part of the book series: Basic Life Sciences ((BLSC,volume 49))

Abstract

Catalases (H2O2:H2O2 oxidoreductase; EC 1.11.1.6) are metalloenzymes that catalyze the elimination of H2O2 according to the equation:

Catalases, together with superoxide dismutases and peroxidases, provide aerobic cells with a defense system for removal of superoxide radical and of hydroperoxides. H2O2 is a cellular toxicant in its own right. Considerable interest in the production of hydroxyl radical by the reduction of H2O2 (equation 2)

mediated by transition metals or other cellular reductants has arisen.

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Authors and Affiliations

  1. Department of Biochemistry, Duke University Medical Center, Durham, North Carolina, 27710, USA

    Wayne F. Beyer Jr. & Irwin Fridovich

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  1. Wayne F. Beyer Jr.
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  2. Irwin Fridovich
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Editor information

Editors and Affiliations

  1. National Bureau of Standards, Gaithersburg, Maryland, USA

    Michael G. Simic

  2. International Life Sciences Institute, Washington, D.C., USA

    Karen A. Taylor

  3. Univesity of California, San Diego, La Jolla, California, USA

    John F. Ward

  4. Max-Planck-Institut für Strahlenchemie, Mülheim a.d. Ruhr, Federal Republic of Germany

    Clemens von Sonntag

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© 1988 Plenum Press, New York

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Beyer, W.F., Fridovich, I. (1988). Catalases—With and Without Heme. In: Simic, M.G., Taylor, K.A., Ward, J.F., von Sonntag, C. (eds) Oxygen Radicals in Biology and Medicine. Basic Life Sciences, vol 49. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5568-7_103

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  • DOI: https://doi.org/10.1007/978-1-4684-5568-7_103

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5570-0

  • Online ISBN: 978-1-4684-5568-7

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