Skip to main content
SpringerLink
Log in

Enhancement of P50 by Inositol Hexa Phosphate Entrapped in Resealed Erythrocytes in Piglets

  • Chapter
Oxygen Transport to Tissue—VI

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 180))

Abstract

Lowering hemoglobin affinity for oxygen improves O2 release capacity but two physiological consequences of an increase in P50 are expected: 1/ an increase in oxygen tension in peripheral capillary blood, 2/ a decrease in blood perfusion in order to minimize the amplitude of change in capillary oxygen tension (GUYTON, 1976). To maintain oxygen uptake, tissular perfusion should be regulated by a vascular constriction and the increased capillary-tissue O2 diffusion would be compensated for by a lowered O2 transport.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Benesch, R.E., Edalji R., Benesch R. 1977, Reciprocal interaction of hemoglobin with oxygen and protons. The influence of allosteric polyanions, Biochemistry 16: 2594–2597

    Article  PubMed  CAS  Google Scholar 

  • Gersonde, K., Nicolau C. 1979, Improvement of the red blood cells O2 release capacity by lipid vesicle-mediated incorporation in inositol hexaphosphate, Blut, 39: 1–7

    Article  PubMed  CAS  Google Scholar 

  • Guyton, A.C. 1976, in “Textbook of medical physiology”, W.B. Saunders Co., Philadelphia

    Google Scholar 

  • Krall, M.A., Bristol J.D., Welch J.E. and Metalfe J. 1978, Physiological effects of lowered blood oxygen affinity in dogs, Respir. Physiol. 33: 263–270

    Article  PubMed  CAS  Google Scholar 

  • Soulard, C.D., Teisseire B.P., Teisseire L.J., Hérigault R.A. 1983, Consequences of an acute increase in P50 anesthetized guinea pigs, Respir. Physiol. 51: 21–30

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. U 138 INSERM Hôpital Henri Mondor, 94010, Créteil, France

    B. Teisseire & M. O. Vallez

  2. ERA 697 CNRS CTS, 37000, Tours, France

    C. Ropars

  3. Lab. Biophys. Mol. CNRS, 45000, Orléans, France

    C. Nicolau & M. Chassaigne

Authors
  1. B. Teisseire
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. C. Ropars
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. C. Nicolau
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. M. O. Vallez
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. M. Chassaigne
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. California Polytechnic State University, San Luis Obispo, California, USA

    Duane Bruley

  2. Western Tumor Medical Group, Van Nuys, California, USA

    Haim I. Bicher

  3. Louisiana Tech University, Ruston, Louisiana, USA

    Daniel Reneau

Rights and permissions

Reprints and permissions

Copyright information

© 1984 Plenum Press, New York

About this chapter

Cite this chapter

Teisseire, B., Ropars, C., Nicolau, C., Vallez, M.O., Chassaigne, M. (1984). Enhancement of P50 by Inositol Hexa Phosphate Entrapped in Resealed Erythrocytes in Piglets. In: Bruley, D., Bicher, H.I., Reneau, D. (eds) Oxygen Transport to Tissue—VI. Advances in Experimental Medicine and Biology, vol 180. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4895-5_65

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-4895-5_65

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4897-9

  • Online ISBN: 978-1-4684-4895-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation