Abstract
The porphyrins are a group of heteroaromatic compounds possessing the parent skeleton shown in structure (1). Although it can be oxidised and reduced, this skeleton in general shows considerable stability. It is characterised by an absorption spectrum possessing a very strong band (the Soret band) at about 400 nm, and (generally) four further bands in the region 500 nm to 600 nm. The electronically excited state (S1) of the porphyrin system follows two pathways, radiative and (initially) nonradiative. The radiative pathway generates the ground state by energy emission (characteristically a red fluorescence, a very sensitive test for the porphyrin system in the absence of a coordinated transition metal ion), while intersystem crossing generates the triplet state, which is capable of sensitising the formation of singlet oxygen.
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© 1984 Plenum Press, New York
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Bonnett, R., Berenbaum, M.C., Kaur, H. (1984). Chemical and Biological Studies on Haematoporphyrin Derivative: An Unexpected Photosensitisation in Brain. In: Andreoni, A., Cubeddu, R. (eds) Porphyrins in Tumor Phototherapy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4721-7_8
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DOI: https://doi.org/10.1007/978-1-4684-4721-7_8
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