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Gender Differences in the Effect of Arachidonate Metabolites

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The Prostaglandin System

Part of the book series: NATO Advanced Study Institutes Series ((ASIAS))

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Abstract

The arachidonate metabolites not only constitute a large class of endogenous substances of high biological activity but they also possess powerful thrombogenic and anti-thrombogenic properties. The greater morbidity and mortality from cardiovascular disease of men as compared to women is well established. Thus, sex differences may be related to gender differentiation among the arachidonate metabolites (1). In this paper we briefly review the current situation.

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References

  1. P. W. Ramwell, E. M. K. Loevey and A. L. Sintetos, Biol. of Reprod., 16: 70–87 (1977).

    Article  CAS  Google Scholar 

  2. L. Hagenfeldt,Ark. Keni., 29: 57 (1968).

    CAS  Google Scholar 

  3. I. Hagenfeldt and J. Wahren, Metabolism, 24: 799 (1975).

    Article  PubMed  CAS  Google Scholar 

  4. L. Hagenfeldt, K. Hagenfeldt and A. Wennmalin, Horm. Metab. Res., 7: 467 (1975).

    Article  PubMed  CAS  Google Scholar 

  5. R. L. Lyman, Prog. Chem. Fats Other Lipids, 9: 195 (1968).

    CAS  Google Scholar 

  6. E. M. K. Loevey, Advances in Prost. and Thromb. Res. Vol. 6–8 (1980).

    Google Scholar 

  7. E. M. K. Loevey, Advances in Prost. and Thromb. Res. Vol. 6–8 (1980).

    Google Scholar 

  8. M. Foegh, Nature, 281: 14 (1979).

    Article  PubMed  CAS  Google Scholar 

  9. A. D. Uzunova, E. R. Ramey and P. W. Ramwell, Prostaglandins, 13: 995 (1977).

    PubMed  CAS  Google Scholar 

  10. J. C. Penhos, M. Montalbert-Smith, F. Rabbani, E. R. Ramey and P. W. Ramwell, Prostaglandins, 18 (1979).

    Google Scholar 

  11. M. Johnson, E. R. Ramey and P. W. Ramwell, Am. J. Physiol., 232: H381 (1977).

    PubMed  CAS  Google Scholar 

  12. A. D. Uzanova, E. R. Ramey and P. W. Ramwell, Am. J. Physiol., 234: H454–459 (1978).

    Google Scholar 

  13. S. Sherry, N. Engl. J. Med., 298: 289 (1968).

    Google Scholar 

  14. Barnett, N. Engl. J. Med., 299: 53 (1978).

    Google Scholar 

  15. M. M. Harris, E. W. Salzman, C. A. Athanacoulis, A. C. Waltman and R. W. DeSanctis, N. Engl. J. Med., 297: 1246 (1977).

    Article  PubMed  CAS  Google Scholar 

  16. J. G. Kelton, J. Hirsh, C. J. Carter and M. R. Buchanan, Blood, 52: 1073 (1978).

    PubMed  CAS  Google Scholar 

  17. A. L. Sintetos, P. W. Ramwell and E. R. Ramey, Fed. Proc., 37: 731 (1978).

    Google Scholar 

  18. P. J. Baker, E. R. Ramey and P. W. Ramwell, Am. J. Physiol., 235: 242 (1978).

    Google Scholar 

  19. J. R. Bedwani and P. B. Marley, Brit. J. Pharmacol., 50: 459 (1974).

    Google Scholar 

  20. H. M. Waldman, I. Alter, P. A. Kot, J. C. Rose and P. W. Ramwell, J. Pharmacol. Exp. Therap., 206: 289 (1978).

    Google Scholar 

  21. H. M. Waldman, I. Alter, P. A. Kot, J. C. Rose, E. R. Ramey and P. W. Ramwell, Proc. Soc. Exp. Biol., 158: 442 (1978).

    PubMed  CAS  Google Scholar 

  22. R. H. Harris, Y. Maddox, E. R. Ramey and P. W. Ramwell, Proc. IV Internat. Prostaglandins Conf., 46 (1979).

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, DC, 20007, USA

    P. W. Ramwell, J. W. Karanian, F. Maggi & E. R. Ramey

Authors
  1. P. W. Ramwell
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  2. J. W. Karanian
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  3. F. Maggi
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  4. E. R. Ramey
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Editor information

Editors and Affiliations

  1. University of Milan, Milan, Italy

    F. Berti

  2. University of Padua, Verona, Italy

    G. P. Velo

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© 1981 Plenum Press, New York

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Ramwell, P.W., Karanian, J.W., Maggi, F., Ramey, E.R. (1981). Gender Differences in the Effect of Arachidonate Metabolites. In: Berti, F., Velo, G.P. (eds) The Prostaglandin System. NATO Advanced Study Institutes Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3896-3_20

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  • DOI: https://doi.org/10.1007/978-1-4684-3896-3_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3898-7

  • Online ISBN: 978-1-4684-3896-3

  • eBook Packages: Springer Book Archive

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