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Effects of 2,3-Diphosphoglycerate on Functional Properties of Hemoglobin and on Glycolysis of Human Erythrocytes

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Oxygen Transport to Tissue — II

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 75))

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Abstract

This report is divided into two parts. The first is concerned with the binding of 2,3-diphosphoglycerate (DPG) to deoxy- and oxyhemoglobin in the absence and presence of CO2 under conditions comparable to those prevailing in intact erythrocytes. In the second part an attempt is made to analyze the mechanism by which glycolysis is inhibited in erythrocytes containing elevated concentrations of DPG.

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© 1976 Plenum Press, New York

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Duhm, J. (1976). Effects of 2,3-Diphosphoglycerate on Functional Properties of Hemoglobin and on Glycolysis of Human Erythrocytes. In: Grote, J., Reneau, D., Thews, G. (eds) Oxygen Transport to Tissue — II. Advances in Experimental Medicine and Biology, vol 75. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3273-2_11

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  • DOI: https://doi.org/10.1007/978-1-4684-3273-2_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3275-6

  • Online ISBN: 978-1-4684-3273-2

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