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Exploitable Aspects of Central Cholinergic Functions, Particularly with Respect to the EEG, Motor, Analgesic and Mental Functions

  • Chapter
Cholinergic Mechanisms and Psychopharmacology

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 24))

Abstract

I seem to be of divided mind on the subject of the exploitation of the cholinergic system. At one time I was warning against the overexploita-tion of the latter (1); at this time, however, I propose that therapeutically, it is underutilized. Actually, a common denominator underlies both feelings. The cholinergic system is almost omnipresent in the CNS and is readily affected by drugs and behavior. Hence, it is easy to ascribe a cholinergic basis to just about any CNS phenomenon. Yet the wrong cholinergic mechanism may be proposed, or the conclusion may be altogether unwarranted (cf. below, and 1). But, for this very reason, the all-pervasiveness of the cholinergic system constitutes the basis for its clinical and basic potential.

Problems Concerning Implications of the Role of Cholinergic System in Behavior

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  1. Department of Pharmacology and Institute for Mind, Drugs and Behavior, Loyola University Medical Center, Maywood, Illinois, 60153, USA

    A. G. Karczmar

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  1. University of California School of Medicine, Los Angeles, California, USA

    Donald J. Jenden

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Karczmar, A.G. (1978). Exploitable Aspects of Central Cholinergic Functions, Particularly with Respect to the EEG, Motor, Analgesic and Mental Functions. In: Jenden, D.J. (eds) Cholinergic Mechanisms and Psychopharmacology. Advances in Behavioral Biology, vol 24. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3096-7_48

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