Abstract
Avian infectious bronchitis virus (IBV) is the etiological agent of a highly contagious respiratory disease. It can cause high mortality, particulary in young chickens. Moreover, the kidneys and reproductive tract are often affected resulting in a drop of egg production in hens. In The Netherlands, infectious bronchitis (IB) used to be controlled by vaccination with the live attenuated virus strains H52 and H120, derived from field isolates (Bijlinga, 1956; Hoekstra and Rispens, 1960). Vaccination with these two strains resulted in protection against virtually all antigenic variants of the virus known at that time (Winterf ield and Fadley, 1975; Winterfield et al., 1976).
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© 1987 Plenum Press, New York
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Niesters, H.G.M., Kusters, J.G., Lenstra, J.A., Spaan, W.J.M., Horzined, M.C., van der Zeijst, B.A.M. (1987). The Neutralization Epitopes on the Spike Protein of Infectious Bronchitis Virus and their Antigenic Variation. In: Lai, M.M.C., Stohlman, S.A. (eds) Coronaviruses. Advances in Experimental Medicine and Biology, vol 218. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1280-2_63
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