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The Function of Drosophila in Genetic Toxicology Testing

  • Chapter
Chemical Mutagens

Part of the book series: Chemical Mutagens

Abstract

Chemical compounds in an ever-increasing variety and kind are constantly being introduced into the human environment. Some of these may affect the genetic material. Such effects, when produced in germ cells, lead to an increase of the genetic load of our descendants, while in somatic cells they may result in the development of malignancies. Recent findings suggest a striking overlap between the mutagenic and carcinogenic potential of chemicals that a distinction between the two tends to become an artificial one.

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  1. Department of Radiation Genetics and Chemical Mutagenesis (Sylvius Laboratory), State University of Leiden, The Netherlands

    E. Vogel & F. H. Sobels

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  1. E. Vogel
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  1. Associated Universities, Inc., Washington, D.C., USA

    Alexander Hollaender

  2. University of Tennessee, Knoxville, Tennessee, USA

    Alexander Hollaender

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Vogel, E., Sobels, F.H. (1976). The Function of Drosophila in Genetic Toxicology Testing. In: Hollaender, A. (eds) Chemical Mutagens. Chemical Mutagens. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0892-8_4

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