Abstract
It is reasonable to assume that viral infection triggers a number of host cell responses; some produced by oncogenic viruses are already well documented (1). It would be surprising that, among viruses lytic for eukaryotic cells, replication would be solely a cytoplasmic event. Since there are data suggesting the existence of signals that reach the cell nucleus after poliovirus infection (2,3), we decided to look for alterations of polysome-associated RNA as one of the early HeLa cell responses to the viral stimulus. This paper will describe the alterations detected and a preliminary characterization of the RNA molecules involved.
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© 1973 Plenum Press, New York
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Contreras, G., Cárdenas, T., Grado, C., Yudelevich, S., Summers, D.F. (1973). Modifications of Polysome-Associated RNA After Poliovirus Infection. In: Kenney, F.T., Hamkalo, B.A., Favelukes, G., August, J.T. (eds) Gene Expression and its Regulation. Basic Life Sciences. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0877-5_34
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DOI: https://doi.org/10.1007/978-1-4684-0877-5_34
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