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Antimutagenesis and Anticarcinogenesis Mechanisms II pp 23–34Cite as

Cancer Prevention: Underlying Principles and Practical Proposals

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Part of the book series: Basic Life Sciences ((BLSC,volume 52))

Abstract

The aim of this symposium on antimutagenesis and anticarcinogenesis is to obtain information on the problem of prevention of human cancer. Carcinogenesis is associated with genetic changes in somatic cells produced by mutagens and carcinogens. The molecular mechanisms of human carcinogenesis are very complicated: multiple genetic changes are often observed in established cancer cell lines, and these changes are generally more numerous in more malignant cancer cells. Completion of the carcinogenic process requires a long time, and precancerous changes often persist for many years.

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Author information

Authors and Affiliations

  1. National Cancer Center, Tsukiji, Chuo-ku, Tokyo, Japan

    Takashi Sugimura

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  1. Takashi Sugimura
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Editor information

Editors and Affiliations

  1. National Institute of Genetics, Mishima, Japan

    Yukiaki Kuroda

  2. University of Kansas, Lawrence, Kansas, USA

    Delbert M. Shankel

  3. United States Environmental Protection Agency, Research Triangle Park, North Carolina, USA

    Michael D. Waters

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© 1990 Plenum Press, New York

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Sugimura, T. (1990). Cancer Prevention: Underlying Principles and Practical Proposals. In: Kuroda, Y., Shankel, D.M., Waters, M.D. (eds) Antimutagenesis and Anticarcinogenesis Mechanisms II. Basic Life Sciences, vol 52. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9561-8_2

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  • DOI: https://doi.org/10.1007/978-1-4615-9561-8_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9563-2

  • Online ISBN: 978-1-4615-9561-8

  • eBook Packages: Springer Book Archive

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