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Bacteriophage DNA as a Model for Correlation of Radical Damage to DNA and Biological Effects

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Mechanisms of DNA Damage and Repair

Part of the book series: Basic Life Sciences ((BLSC,volume 189))

Abstract

The radiolysis of neutral water by γ-rays can be summarized by means of the following symbolical expression:

$${H_2}O\,\, \to 0.70\,\,{H_2}{O_2}\, + \,0.45\,{H_2}|\, + \,2.7\,\dot OH\, + \,2.65\,e_{aq}^ - \, + \,0.55\,\dot H$$
(7)

The figures in this equation represent the radiation-chemical yields of the products, i.e. the number of molecules or radicals produced per 100 eV of absorbed energy.

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Author information

Authors and Affiliations

  1. Biophysics Department, Free University, Amsterdam, The Netherlands

    Joh Blok & H. Loman

Authors
  1. Joh Blok
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  2. H. Loman
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Editor information

Editors and Affiliations

  1. National Bureau of Standards, Gaithersburg, Maryland, USA

    Michael G. Simic

  2. Chemistry Department, American University, Washington, D.C., USA

    Michael G. Simic

  3. Johns Hopkins University, Baltimore, Maryland, USA

    Lawrence Grossman

  4. New York University Medical Center, New York, New York, USA

    Arthur C. Upton

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© 1986 Plenum Press, New York

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Blok, J., Loman, H. (1986). Bacteriophage DNA as a Model for Correlation of Radical Damage to DNA and Biological Effects. In: Simic, M.G., Grossman, L., Upton, A.C., Bergtold, D.S. (eds) Mechanisms of DNA Damage and Repair. Basic Life Sciences, vol 189. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9462-8_9

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  • DOI: https://doi.org/10.1007/978-1-4615-9462-8_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9464-2

  • Online ISBN: 978-1-4615-9462-8

  • eBook Packages: Springer Book Archive

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