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Regional Changes in Metabolism in Hypoxia-Ischemia

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Tissue Hypoxia and Ischemia

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 78))

Abstract

The purpose of this study is to describe regional metabolic changes following an episode of cerebral ischemia in the cat. Regional characterization of metabolic derangements is imperative because it is unlikely that cerebral blood flow is uniformly reduced in most hypoxic-ischemic episodes.1, 2, 3 Furthermore, neurons in discrete anatomic regions such as hippocampus or arterial border zones4 are selectively vulnerable to hypoxia-ischemia. Consequently, we have investigated regional alterations of cerebral metabolites in a model of incomplete ischemia (oligemia).

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References

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© 1977 Plenum Press, New York

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Welsh, F.A., O’Connor, M.J., Rieder, W., Marcy, V.R. (1977). Regional Changes in Metabolism in Hypoxia-Ischemia. In: Reivich, M., Coburn, R., Lahiri, S., Chance, B. (eds) Tissue Hypoxia and Ischemia. Advances in Experimental Medicine and Biology, vol 78. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9035-4_23

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  • DOI: https://doi.org/10.1007/978-1-4615-9035-4_23

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9037-8

  • Online ISBN: 978-1-4615-9035-4

  • eBook Packages: Springer Book Archive

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