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Size exclusion chromatography of small molecules

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Size Exclusion Chromatography

Abstract

SEC has long been recognized as a major technique for the characterization of materials of high molecular mass, i.e., polymers. The application to small molecules (molecular mass ≤ 1000) has received much less attention. One of the first applications of SEC in the authors’ laboratory was the separation of dimer acid (MW c.500) from a petroleum fuel fraction in 1968, and there has been a constant succession of subsequent analytical applications as well as the more conventional projects on polymer characterization.

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Hillman, D.E., Heathcote, C. (1989). Size exclusion chromatography of small molecules. In: Hunt, B.J., Holding, S.R. (eds) Size Exclusion Chromatography. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7861-1_6

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  • DOI: https://doi.org/10.1007/978-1-4615-7861-1_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-7863-5

  • Online ISBN: 978-1-4615-7861-1

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