Abstract
In 1959 Prinzmetal et al1 described a variant form of angina, which, in contrast with the more common effort angina, occurs exclusively or predominantly at rest, often without apparent cause, and is characterized by elevation, rather than depression, of the ST-segment on the electrocardiogram (ECG). The authors hypothesized that this form of angina was caused by an increase in “tonus” at the site of a subcritical coronary stenosis.1 Indeed, no increase in the hemodynamic determinants of myocardial oxygen consumption can be detected by continuous hemodynamic monitoring before the appearance of ischemia.2,3
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References
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Maseri, A., Lanza, G.A. (1999). Vasospastic Angina. In: Contemporary Concepts in Cardiology. Developments in Cardiovascular Medicine, vol 217. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5007-5_6
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DOI: https://doi.org/10.1007/978-1-4615-5007-5_6
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