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Molecular switches that govern the balance between proliferation and apoptosis

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Progress in Cell Cycle Research

Part of the book series: Progress in Cell Cycle Research ((PCCR))

Abstract

Tissue modelling during embryogenesis and tissue homeostasis during adult life is governed by a dynamic equilibrium between growth and programmed cell death (apoptosis). Growth control and apoptosis are intimately associated, and a disturbance of the balance between these two processes often leads to pathological situations, such as for example cell accumulations in cancer.

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  1. Department of Molecular Cell Biology and Genetics, University of Maastricht, P.O. Box 616, 6200 MD, Maastricht, The Netherlands

    Bert Schutte & Frans C. S. Ramaekers

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  1. Centre National de la Recherche Scientifique, Roscoff, France

    Laurent Meijer  & Armelle Jézéquel  & 

  2. Centre National de la Recherche Scientifique, Université Paul Sabatier, Toulouse, France

    Bernard Ducommun

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Schutte, B., Ramaekers, F.C.S. (2000). Molecular switches that govern the balance between proliferation and apoptosis. In: Meijer, L., Jézéquel, A., Ducommun, B. (eds) Progress in Cell Cycle Research. Progress in Cell Cycle Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4253-7_18

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