Abstract
A number of recent studies have implicated the involvement of ferritin iron in oxygen radical reactions. Hemosiderin has long been thought to be a degradation product of ferritin. A recent series of papers have indicated that oxygen radical damage to proteins result in an increase in susceptibility to a novel proteolytic system. We suggest a possible relationship between radical damage to ferritin and hemosiderin via this proteolytic system.
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Grady, J.K., Chasteen, N.D. (1991). Some Speculations on the Role of Oxyradicals in the Conversion of Ferritin to Hemosiderin. In: Frankel, R.B., Blakemore, R.P. (eds) Iron Biominerals. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3810-3_22
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DOI: https://doi.org/10.1007/978-1-4615-3810-3_22
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