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Fatty acid-binding protein and its relation to fatty acid oxidation

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Cellular Fatty Acid-Binding Proteins II

Part of the book series: Developments in Molecular and Cellular Biochemistry ((DMCB,volume 10))

Abstract

A relation between fatty acid oxidation capacity and cytosolic FABP content was found in heart and various muscles of the rat. Other tissues do not show such a relation, since they are involved in more or other pathways of fatty acid metabolism. At postnatal development FABP content and fatty acid oxidation capacity rise concomitantly in heart and quadriceps muscle in contrast to in liver and kidney. A dietary fat content of 40 en. % increased only the FABP content of liver and adipose tissue. Peroxisomal proliferators increased fatty acid oxidation in both liver and kidney, but only the FABP content of liver, and had no effect on heart and skeletal muscle. The FABP content of muscle did not show adaptation to various conditions. Only it increased in fast-twitch muscles upon chronic electrostimulation and endurance training.

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Authors and Affiliations

  1. Department of Biochemistry, University of Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands

    J. H. Veerkamp & H. T. B. van Moerkerk

Authors
  1. J. H. Veerkamp
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  2. H. T. B. van Moerkerk
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Editor information

Editors and Affiliations

  1. Department of Physiology, University of Limburg, Maastricht, The Netherlands

    Jan F. C. Glatz  & Ger J. van der Vusse  & 

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© 1993 Springer Science+Business Media Dordrecht

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Veerkamp, J.H., van Moerkerk, H.T.B. (1993). Fatty acid-binding protein and its relation to fatty acid oxidation. In: Glatz, J.F.C., van der Vusse, G.J. (eds) Cellular Fatty Acid-Binding Proteins II. Developments in Molecular and Cellular Biochemistry, vol 10. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3096-1_13

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  • DOI: https://doi.org/10.1007/978-1-4615-3096-1_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6353-8

  • Online ISBN: 978-1-4615-3096-1

  • eBook Packages: Springer Book Archive

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