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Role of Selenium in Immune Responsiveness and Disease Resistance

  • Chapter
Nutrition and Immunology

Part of the book series: Human Nutrition ((HUNU))

Abstract

Although selenium was established as an essential nutrient for mammals in 1957, it wasn’t until the early 1970s that a true biological function for the element was recognized (Schwarz and Foltz, 1957; Schwarz et al., 1957; Rotruck et al., 1972). Rotruck et al. (1973) established that selenium is an integral component of the metalloenzyme glutathione peroxidase, and, as such, plays an important role in the cellular antioxidant defense system.

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Authors and Affiliations

  1. National Animal Disease Center, ARS, United States Department of Agriculture, Ames, Iowa, 50010, USA

    Judith R. Stabel

  2. Department of Animal Science and Interdepartmental Nutrition Program, North Carolina State University, Raleigh, North Carolina, 27695, USA

    Jerry W. Spears

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  1. Judith R. Stabel
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  1. Wayne State University, Detroit, Michigan, USA

    David M. Klurfeld

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Stabel, J.R., Spears, J.W. (1993). Role of Selenium in Immune Responsiveness and Disease Resistance. In: Klurfeld, D.M. (eds) Nutrition and Immunology. Human Nutrition. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2900-2_16

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  • DOI: https://doi.org/10.1007/978-1-4615-2900-2_16

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6257-9

  • Online ISBN: 978-1-4615-2900-2

  • eBook Packages: Springer Book Archive

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