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Circadian Rhythmometric Studies on the Low Molecular Weight Urinary Inhibitors of Calcium Oxalate Urolithiasis

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Urolithiasis 2
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Abstract

The possible significance of low molecular weight inhibitors (Mg, citrate and pyrophosphate) in the prevention of calcium oxalate urolithiasis has been emphasized1. Estimation of total 24 h excretion of urinary inhibitors in stone-formers (SF) will not reveal any circadian fluctuations. However, measurements of 3-hourly urine samples collected over a 24 h span should give a better picture of their circadian rhythmicity, which may help to expose any urinary biological abnormalities present therein. Therefore, the circadian rhythm of the 3 h excretion of Mg, citrate and pyrophosphate, and urinary inhibitory activity towards calcium oxalate monohydrate (COM) crystallization in SF and healthy subjects (N), were investigated.

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© 1994 Springer Science+Business Media New York

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Wangoo, D., Rattan, V., Thind, S.K., Gupta, G.S., Nath, R. (1994). Circadian Rhythmometric Studies on the Low Molecular Weight Urinary Inhibitors of Calcium Oxalate Urolithiasis. In: Ryall, R., Bais, R., Marshall, V.R., Rofe, A.M., Smith, L.H., Walker, V.R. (eds) Urolithiasis 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2556-1_139

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  • DOI: https://doi.org/10.1007/978-1-4615-2556-1_139

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6091-9

  • Online ISBN: 978-1-4615-2556-1

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