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The Role of Cytokines in the Pathogenesis of Pulmonary Langerhans’ Cell Histiocytosis

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Dendritic Cells in Fundamental and Clinical Immunology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 378))

Abstract

Langerhans’ cell histiocytosis (LCH) is characterized by an accumulation and/or proliferation of cells with a Langerhans’ cell (LC) phenotype. Immunohistochemically, the cells express CDla and S-100, and with electron microscopy Birbeck’ granules can be identified in the cytoplasm of the LCH cells.

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References

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Author information

Authors and Affiliations

  1. Departments of Pathology, University Hospital of Groningen, Oostersingel 63, 9713 EZ, Groningen, The Netherlands

    Jan H. de Graaf & Wim Timens

  2. Departments of Pulmonology, University Hospital of Groningen, Oostersingel 63, 9713 EZ, Groningen, The Netherlands

    Gregor P. M. Mannes

  3. Departments of Pediatric Oncology, University Hospital of Groningen, Oostersingel 63, 9713 EZ, Groningen, The Netherlands

    Rienk Y. J. Tamminga & Willem A. Kamps

Authors
  1. Jan H. de Graaf
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  2. Gregor P. M. Mannes
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  3. Rienk Y. J. Tamminga
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  4. Willem A. Kamps
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  5. Wim Timens
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Editor information

Editors and Affiliations

  1. Laboratory for Immunological Research, Schering-Plough, Dardilly, France

    Jacques Banchereau

  2. INSERM U346, Hôpital Edouard Herriot, Lyon, France

    Daniel Schmitt

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© 1995 Springer Science+Business Media New York

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de Graaf, J.H., Mannes, G.P.M., Tamminga, R.Y.J., Kamps, W.A., Timens, W. (1995). The Role of Cytokines in the Pathogenesis of Pulmonary Langerhans’ Cell Histiocytosis. In: Banchereau, J., Schmitt, D. (eds) Dendritic Cells in Fundamental and Clinical Immunology. Advances in Experimental Medicine and Biology, vol 378. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1971-3_120

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  • DOI: https://doi.org/10.1007/978-1-4615-1971-3_120

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5811-4

  • Online ISBN: 978-1-4615-1971-3

  • eBook Packages: Springer Book Archive

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