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Communication of Islet Cells: Molecules and Functions

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Molecular Basis of Pancreas Development and Function

Part of the book series: Endocrine Updates ((ENDO,volume 11))

Abstract

The appearance of multicellular systems, approximately 800 million years ago, was dependent on the ability of cells to develop mechanisms for adhesion to neighbours and to components of an extracellular matrix, as well as mechanisms for exchange of signals between adjacent and distant cells. With evolution, such mechanisms diversified and have been progressively integrated into a complex regulatory network, whereby individual cells sense the state of activity of their neighbours and adapt their own level of function.

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Authors and Affiliations

  1. University of Geneva Medical School, CH-1211 Geneva 4, Switzerland

    Paolo Meda M.D. & Domenico Bosco Ph.D.

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  1. Paolo Meda M.D.
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  2. Domenico Bosco Ph.D.
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Editors and Affiliations

  1. Laboratory of Molecular Endocrinology, Howard Hughes Medical Institute, Massachusetts General Hospital, Boston, MA

    Joel F. Habener M.D.

  2. Department of Medicine, Clinical and Molecular Endocrinology, New York University Medical Center, New York, NY

    Mehboob A. Hussain M.D.

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© 2001 Springer Science+Business Media New York

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Meda, P., Bosco, D. (2001). Communication of Islet Cells: Molecules and Functions. In: Habener, J.F., Hussain, M.A. (eds) Molecular Basis of Pancreas Development and Function. Endocrine Updates, vol 11. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1669-9_8

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  • DOI: https://doi.org/10.1007/978-1-4615-1669-9_8

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  • Online ISBN: 978-1-4615-1669-9

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