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Staphylococcus aureus Vaccine

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New Bacterial Vaccines

Part of the book series: Medical Intelligence Unit ((MIUN))

Summary

Staphylococcus aureus is frequently isolated from both hospital-acquired and community-acquired infections, and the emergence of antibiotic resistance among clinical isolates has made treatment of staphylococcal infections difficult. This scenario has sparked renewed interest in the development of a vaccine for individuals at high risk for staphylococcal infections. As part of the effort to develop a multicomponent vaccine against S. aureus, several vaccine candidates are being evaluated in clinical trials or in animal models of infection. The most promising candidates to date include the capsular polysaccharides type 5 and 8, the adhesins (fibronectin-binding protein, collagen-binding protein, and fibrinogen-binding protein [clumping factor]), and a nontoxic alpha-toxin mutant.

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Authors
  1. Jean C. Lee
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© 2003 Springer Science+Business Media New York

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Lee, J.C. (2003). Staphylococcus aureus Vaccine. In: New Bacterial Vaccines. Medical Intelligence Unit. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0053-7_18

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  • DOI: https://doi.org/10.1007/978-1-4615-0053-7_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4902-0

  • Online ISBN: 978-1-4615-0053-7

  • eBook Packages: Springer Book Archive

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