Skip to main content
SpringerLink
Log in

Immunotherapy for Allergic Rhinitis

  • Reference work entry
  • First Online:
Encyclopedia of Medical Immunology

  • 167 Accesses

Synonyms

Allergen immunotherapy; Allergen-specific desensitization; Allergic rhinitis; Allergy immunotherapy; Allergy injections; Allergy shots; Hay fever; Hyposensitization; Immunotherapy

Definition

Immunotherapy for allergic rhinitis involves the long-term administration of specific environmental allergens to individuals sensitized to these allergens through IgE-mediated mechanisms for the purpose of diminishing or eliminating the allergic symptoms caused by exposure to these allergens (Cox et al. 2011).

Background

Allergic rhinitis affects an estimated 600 million individuals worldwide, including 200 million individuals with associated asthma (Calderon et al. 2011). Individuals who have allergic rhinitis have symptoms such as nasal discharge, nasal congestion, nasal itching, sneezing, and/or postnasal drainage (Nelson 2009). Many people with allergic rhinitis have symptoms that can be satisfactorily controlled with readily available medications such as antihistamines and nasal...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 549.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 849.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Calderon MA, Alves B, Jacobson M, et al. Allergen injection immunotherapy for seasonal allergic rhinitis. Cochrane Database Syst Rev. 2007;(1):Art No:CD001936.

    Google Scholar 

  • Calderon MA, Casale TB, Togias A, et al. Allergen-specific immunotherapy for respiratory allergies: from meta-analysis to registration and beyond. J Allergy Clin Immunol. 2011;127:30–8.

    PubMed  Google Scholar 

  • Cox L, Nelson H, Locke R, et al. Allergen immunotherapy: a practice parameter third update. J Allergy Clin Immunol. 2011;127:S1–55.

    PubMed  Google Scholar 

  • Nelson HS. Immunotherapy for inhalant allergens. In: Adkinson NF, Bochner BS, Busse WW, Holgate ST, Lemanske RF, Simons FER, editors. Middleton’s allergy: principles and practice. Philadelphia: Elsevier; 2009. p. 1657–77.

    Google Scholar 

  • Ross RN, Nelson HS, Finegold I. Effectiveness of specific immunotherapy in the treatment of allergic rhinitis: an analysis of randomized, prospective, single- or double-blind, placebo-controlled studies. Clin Ther. 2000;22:342–50.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Internal Medicine, Division of Allergy and Pulmonary Medicine, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA

    Thanai Pongdee

Authors
  1. Thanai Pongdee
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Thanai Pongdee .

Editor information

Editors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia

    Ian R. Mackay

  2. Center for Autoimmune Disease Research, Department of Molecular Microbiology and Immunology, Department of Pathology, Johns Hopkins University, Baltimore, MD, USA

    Noel R. Rose

  3. Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, James A. Haley Veterans' Hospital, Tampa, FL, USA

    Dennis K. Ledford

  4. Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, James A. Haley Veterans' Hospital, Tampa, FL, USA

    Richard F. Lockey

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag Berlin Heidelberg

About this entry

Cite this entry

Pongdee, T. (2014). Immunotherapy for Allergic Rhinitis. In: Mackay, I.R., Rose, N.R., Ledford, D.K., Lockey, R.F. (eds) Encyclopedia of Medical Immunology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9194-1_529

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-9194-1_529

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-9193-4

  • Online ISBN: 978-1-4614-9194-1

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation