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Methyldibromo Glutaronitrile, Contact Allergy to

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  • First Online:
Encyclopedia of Medical Immunology

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Synonyms

Contact dermatitis; Methyldibromo glutaronitrile

Methyldibromo glutaronitrile is a potent contact allergen, which is used as a preservative in a wide variety of products because of its antimicrobial properties. It can be found in all kinds of cosmetic and personal care products such as body, face, and hand lotions, sunscreens, baby lotions, shower gels, shampoos, massage oils, and even in toilet paper. Furthermore, it is also a common component of paints, cutting and drilling oils, polishes, cleaning agents, coolants, and glues. Because of its widespread appearance and increased sensitizing potential, it has been banned in leave-on products in Europe. Skin contact elicits a cutaneous delayed-type hypersensitivity reaction with erythema, swelling, vesicles, crusting, and desquamation in sensitized people.

Cross-References

Allergic Contact Dermatitis

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Author information

Authors and Affiliations

  1. Department of Dermatology and Allergology, Philipps University Marburg, Marburg, Germany

    Wolfgang Pfützner

Authors
  1. Wolfgang Pfützner
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Correspondence to Wolfgang Pfützner .

Editor information

Editors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia

    Ian R. Mackay

  2. Center for Autoimmune Disease Research, Department of Molecular Microbiology and Immunology, Department of Pathology, Johns Hopkins University, Baltimore, MD, USA

    Noel R. Rose

  3. Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, James A. Haley Veterans' Hospital, Tampa, FL, USA

    Dennis K. Ledford

  4. Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, James A. Haley Veterans' Hospital, Tampa, FL, USA

    Richard F. Lockey

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© 2014 Springer-Verlag Berlin Heidelberg

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Pfützner, W. (2014). Methyldibromo Glutaronitrile, Contact Allergy to. In: Mackay, I.R., Rose, N.R., Ledford, D.K., Lockey, R.F. (eds) Encyclopedia of Medical Immunology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9194-1_470

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  • DOI: https://doi.org/10.1007/978-1-4614-9194-1_470

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-9193-4

  • Online ISBN: 978-1-4614-9194-1

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