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Method of Direct Multiparticle Simulation of Protein Interactions

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Mathematical Biophysics

Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

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Abstract

Electron transport processes in the photosynthetic and mitochondrial membranes of a cell are mediated by protein–protein complexes and mobile carriers. For a general kinetic description of these reactions mathematical models have been developed where some modifications of the mass action law are used. The rate constants of biochemical reactions of protein–protein association and concentrations of donor and acceptor protein molecules serve as parameters in these kinetic models. Rate constant values are determined under various conditions (e.g., different pH, ionic strength) and evaluated according to experimental data; therefore, the corresponding kinetic models are essentially phenomenological since their rate constants have effective values.

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Authors and Affiliations

  1. Department of Biophysics, Lomonosov Moscow State University, Moscow, Russia

    Andrew Rubin & Galina Riznichenko

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  1. Andrew Rubin
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  2. Galina Riznichenko
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Rubin, A., Riznichenko, G. (2014). Method of Direct Multiparticle Simulation of Protein Interactions . In: Mathematical Biophysics. Biological and Medical Physics, Biomedical Engineering. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-8702-9_13

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  • DOI: https://doi.org/10.1007/978-1-4614-8702-9_13

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  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4614-8701-2

  • Online ISBN: 978-1-4614-8702-9

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