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Integrating Systems and Synthetic Biology

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Developing Biofuel Bioprocesses Using Systems and Synthetic Biology

Part of the book series: SpringerBriefs in Systems Biology ((BRIEFSBIOSYS))

Abstract

Research approaches to developing biofuel processes involve the integration of different aspects of biology, chemistry, and engineering. Recent developments in knowledge and technology have enabled a shift away from discovery-based, trial-and-error design to a more directed prospective design process. Systems biology and synthetic biology have contributed to this shift in methodologies in complementary ways. Systems biology provides much of the knowledge background and whole-cell modeling methods to enable cellular-level design. Synthetic biology provides DNA-level detail to design strategies and the experimental methods to directly implement proposed designs. Application of methodologies from these two fields provides a strong framework for cellular and molecular biological engineering.

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Authors and Affiliations

  1. Virginia Commonwealth University, W. Main Street 601, Richmond, 23284, VA, USA

    Sylvia M. Clay & Stephen S. Fong

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  1. Sylvia M. Clay
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  2. Stephen S. Fong
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Correspondence to Sylvia M. Clay .

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Clay, S.M., Fong, S.S. (2013). Integrating Systems and Synthetic Biology. In: Developing Biofuel Bioprocesses Using Systems and Synthetic Biology. SpringerBriefs in Systems Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5580-6_6

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